Morcellation, a technique often used to remove fibroids through small incisions, has raised safety concerns due to the risk of spreading occult cancer cells, such as leiomyosarcoma
Vitamin B6 also affects GSH status of human patients
5.1 Mitochondria-targeted antioxidants and metabolic modulators Many natural compounds exert their therapeutic effects by improving mitochondrial function
Depletion of GSH leads to oxidation of protein sulfhydryl groups, resulting in the formation of intra- and inter-molecular cross-links
Zhang X, Selvaraju K, Saei AA, DArcy P, Zubarev RA, Arner ES, Linder S (2019) Repurposing of auranofin: Thioredoxin reductase remains a primary target of the drug
As we get older, our natural production of glutathione declines and our stores become depleted